Newsletters

Vapourtec Spring Newsletter 2024

Date: April 2024

Included in this newsletter:

• Photochemical add-on for CSTR module
• Release of Stage 4 R-Series software
• Brand new application note
• Interview with Prof. Thomas Wirth
• 4 upcoming events Vapourtec will be attending to showcase our equipment
• 6 selected publications utilising Vapourtec flow chemistry systems

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Vapourtec Winter 2023/24 Newsletter

Date: January 2024

Included in this newsletter:

• NEW product launch: PS-30 pilot scale peptide synthesis
• NEW product launch: SF10+
• More resources now available online
• 2 new application notes
• 4 upcoming events Vapourtec will be attending to showcase our equipment
• 6 selected publications utilising Vapourtec flow chemistry systems

Vapourtec Summer 2023 Newsletter – 20 Year Special Edition

Date: September 2023

Included in this newsletter:

• NEW product launch: CSTR flow reactor
• NEW product launch: Range of fast-flow peptide synthesizers
• Twenty years of Vapourtec
• Vapourtec reach major publication milestone
• 4 upcoming events Vapourtec will be attending to showcase our equipment
• 6 selected publications utilising Vapourtec flow chemistry systems

Vapourtec Winter 2023 Newsletter – Pilot scale developments from Vapourtec

Date: January 2023

Included in this newsletter:

• Pilot scale developments from Vapourtec
• Vapourtec launch innovative stage 3 R-Series software with OPC-UA
• 2 upcoming events Vapourtec will be attending to showcase equipment
• 6 selected publications utilising Vapourtec flow chemistry systems

Vapourtec Autumn 2022 Newsletter – The Vapourtec RS-500 Continuous Flow Solid Peptide Synthesis

Date: October 2022

Included in this newsletter:

• The Vapourtec RS-500 Continuous Flow Solid Phase Peptide Synthesis
• 5 upcoming events Vapourtec will be attending to showcase our equipment
• 6 selected publications utilising Vapourtec flow chemistry systems

Vapourtec Summer 2022 Newsletter – Stage 3 of the R-Series software with OPC UA & application notes 72 & 73

Date: July 2022

Included in this newsletter:

• New R-Series software launch
• 6 selected publications utilising Vapourtec flow chemistry systems
• 2 new application notes
• 6 upcoming events Vapourtec will be attending to showcase our equipment

Vapourtec Summer 2021 Newsletter – Electrochemistry teaching module launch & new easy-HC10 in situ biocide system

Date: August 2021

Included in this newsletter:

• 2 new product news items
• 4 new application notes
• 6 selected publications utilising Vapourtec flow chemistry systems
• New R-Series software is introduced

Vapourtec Summer 2020 Newsletter – New solid phase peptide synthesis reactor and accessories

Date: August 2020

Included in this newsletter:

• 2 new product news items
• 4 new application notes
• 8 new publications utilising Vapourtec systems
• A milestone achievement is highlighted

Vapourtec Summer 2019 Newsletter – High power LEDs & 2 new electrochemical application notes

Date: August 2019

Included in this newsletter:

• 4 new product news items
• 2 new application notes
• 6 new publications utilising Vapourtec systems
• 4 events featuring Vapourtec systems

Vapourtec autumn 2018 Newsletter – Ion product launch & 6 new publications

Date: October 2018

Included in this newsletter:

• 2 new product launches
• 1 new application note
• 6 new publications utilising Vapourtec systems
• 4 events featuring Vapourtec systems

Vapourtec summer 2018 Newsletter – 3 new application notes & 6 new publications

Date: June 2018

Included in this newsletter:

• 3 new product news
• 3 new application notes
• 6 new publications utilising Vapourtec systems
• 4 events featuring Vapourtec systems

Vapourtec spring 2018 Newsletter – new application notes & 5 new publications

Date: March 2018

Included in this newsletter:

• 2 New product announcements
• Flow chemistry pumps – new features
• 1 new application note
• 5 new publications utilising Vapourtec systems

Vapourtec Winter 2017 Newsletter – 1 new application note & 5 new publications

Date: December 2017

Included in this newsletter:

• 3 new product news
• 4 events featuring Vapourtec systems
• 1 new application note
• 5 new publications utilising Vapourtec systems

Vapourtec Autumn Newsletter 2017 – Peptide synthesis capability and more

Date: November 2017

Included in this newsletter:

• Exciting developments in flow peptide synthesis
• Versatile features added to Vapourtec’s product range
• Interesting news stories
• Newly released flow publications and application notes

6 new publications & 1 new application note – Vapourtec Summer Newsletter 2017

Date: July 2017

Included in this newsletter:

• 6 new publications utilising Vapourtec systems
• 1 new application note
• 4 new product announcements
• 4 events featuring Vapourtec systems

6 new publications & 4 new application notes – Vapourtec Spring Newsletter 2017

Date: April 2017

Included in this newsletter:

• 6 new publications utilising Vapourtec systems
• 4 new application notes
• 4 new product announcements
• 4 events featuring Vapourtec systems

6 new publications & 1 new application – Vapourtec Winter Newsletter 2016

Date: November 2016

Included in this newsletter:

• 6 new publications utilising Vapourtec systems
• 1 new application
• 4 new product announcements
• 1 event review
• Events information

6 new publications & 1 new application – Vapourtec Autumn Newsletter 2016

Date: September 2016

Included in this newsletter:

• 6 new publications utilising Vapourtec systems
• 1 new application
• 4 new product announcements
• Applications support
• Events information

8 new publications & 4 application notes – Vapourtec Spring Newsletter 2016

Date: May 2016

Included in this newsletter:

• 8 new publications utilising Vapourtec systems
• 4 new application notes
• New reactor with full length static mixer
• New reactor for immobilised photo catalysts
• Low pressure mercury lamps now available for UV-150
• New set of long-pass filters for UV-150

New Publications & New Features – Vapourtec Spring Newsletter

Date: April 2015

Included in this newsletter:

• 8 new publications utilising Vapourtec systems
• New suspension/slurry pump module
• Nanoparticle synthesis under flow conditions
• LED continuous flow photochemical reactor
• Further growth in flow chemistry
• Continuous liquid-liquid extraction

12 new publications – Vapourtec Winter 2014 newsletter

Date: December 2014

Included in this newsletter:

• Introducing the R2-S new Suspension / light slurry pump module
• Continuous flow of publications tops 150 for Vapourtec systems
• Vapourtec sees growth in India
• Flow v batch Photochemistry – a like-for-like comparison
• Meetings, conferences, or exhibitions where you can see Vapourtec products and talk to Vapourtec staff
• Synthesis of Artemisinin via the Photooxidation of Dihydroartemisinic Acid
• Preparation of Silver Nanoparticles under Continuous Flow Conditions
• 12 new publications in this issue

15 new flow chemistry publications – Vapourtec spring newsletter

Date: March 2014

Welcome to our March e-newsletter! We’re excited to announce that Vapourtec just installed its 200th R-Series system. We’d like to say a big thank you to all our customers, who have moved chemistry forward enormously and helped Vapourtec reach this significant milestone.

New Tools for Easier Flow Chemistry

Date: August 2013

Included in this newsletter:

• E-Series tools. We take a look at the simple but powerful tools built into every E-Series flow chemistry system, including the ability to run an automated flow experiment with no manual intervention
• Meetings, conferences, or exhibitions where you can see Vapourtec products and talk to Vapourtec staff
• A New Publication Showing the Use of the E-Series System for Organometallic Chemistry
• Alkyl-Aryl Negishi Cross-Coupling in Flow
• Palladium-Catalyzed Decarboxylative Couplings using Oxygen as the Oxidant
• Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors
• Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis
• Rapid Generation of Isothiocyanates in Flo

Organometallics and Flow Chemistry teaching

Date: February 2013

Included in this newsletter:

• The Vapourtec E-Series shows what it can do with organometallic reagents
• E-Series teaching materials – ready made undergraduate lab course, free with each instrument
• Chromium Arene Synthesis
• Butyl Lithium reactions with the new E-Series
• Grignard Reactions with the new E-Series
• the University of Montreal makes big flow chemistry investment
• Two very informative webinars you might want to check out
• See what’s coming up this year on the flow chemistry event calendar
• Continuous Synthesis and Use of N-Heterocyclic Carbene Copper(I) Complexes from Insoluble Cu2O
• Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions
• Synthesis of RAFT Block Copolymers in multi-stage flow
• Synthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical ThiolEne Coupling
• Ozonolysis of Some Complex Organic Substrates in Flow
• Synthesis of Imatinib and analogues utilising flow

Neat Synthesis: Faster, greener and cheaper

Date: November 2012

Included in this newsletter:

• More solvent free chemistry, offering both higher throughput and a much greener approach
• Some high-pressure flow chemistry, using liquefied gaseous reagents at elevated temperatures
• A new application showcasing the Vapourtec acid-resistant gas/liquid membrane reactor
• Flow synthesis of organic electronic materials
• Preparation of arene chromium tricarbonyl complexes in flow
• Light-Initiated preparation of functionalized polystyrene monoliths

A breakthrough in flow chemistry …

Date: August 2012

Included in this newsletter:

• Nitro reduction with iron granules
• Amidocarbonylation with CO using a gas/liquid reactor
• Continuous pumped fluorination with DAST
• Continuous flow synthesis and inline purification using simulated moving bed (SMB)
• Continuous end group removal of polymers using a RAFT process
• A “Catch-React-Release” Method for the Flow Synthesis of 2-Aminopyrimidines
• Asymmetric Homogeneous Hydrogenation in Flow using a Tube-in-Tube Reactor and more

Solvent Free Reactions: Very high throughput

Date: September 2012

Included in this newsletter:

• We look “under the hood” of the Vapourtec V-3 pump, (Above) which is at the heart of the new E-Series flow chemistry system. Several of you have asked about the technology behind it, and here we describe how it works, and what it makes possible.
• An example of solvent-free (ie neat) synthesis, with throughput in excess of 400g/hr
• O-Methylation of a carboxylic acid with TMS diazomethane

Automated medchem and flow hydrogenation

Date: May 2012

Included in this newsletter:

• An exciting new Vapourtec collaboration in India
• A case study of a fully automated discovery platform for a hit to lead optimisation
• New publications
• Vapourtec and Pi-Process Intensification Experts LLP
• Max Planck institute ramps up their flow chemistry work
• Continuous Flow Hydrogenation with the Vapourtec gas/liquid reactor
• Case Study – Cyclofluidic Ltd
• Events diary
• Publications

Mixing & dispersion, ionic liquids, and high pressures

Date: March 2012

Included in this newsletter:

• A must-read publication from MIT examining in depth the issues of mixing, dispersion, and scaleup in continuous flow reactors
• A new Vapourtec/METTLER TOLEDO joint white paper showing the use of the FlowIR^TM system in conjunction with the Vapourtec R Series^TM System for real-time monitoring of reaction output
• The unveiling of the new Vapourtec High-Pressure flow system
• METTLER TOLEDO FlowIR™ / Vapourtec white paper
• The new Vapourtec High-Pressure Pump Module
• Synthesizing ionic liquids using the Vapourtec R Series^TM
• Discount registration for the Flow Chemistry Congress meeting in Boston
• Mixing, dispersion, and scaleup in continuous flow reactors
• Example of scale up to > 2kg
• Phase Transfer Catalysis in flow
• Two reviews looking at the flow chemistry world from different perspectives

New Application Notes and Tropical Diseases

Date: January 2012

Included in this newsletter:

• New low-cost flow route for synthesis of key anti-malarial drug announced
• Revisiting the cooled column
• Vapourtec Flow Workshop
• 3 new application notes now available
• Where you can meet Vapourtec in 2012 (updated)
• Flow synthesis of the anti-malarial drug Artemisinin
• Homogeneous catalyst produced on demand from a solid packed bed
• Plus three more interesting new papers
• Plus a new review of flow technology

FTIR integration, dual reactors and exotherms

Date: November 2011

Included in this newsletter:

• Integration of METTLER TOLEDO FlowIR(TM) with Vapourtec system
• New “Dual Core” coil reactors – two reactors in one
• New application notes available, showing how to use the gas/liquid reactor
• How to safely investigate and actually quantify exotherms with the R Series
• Where you can see Vapourtec in 2012 (and some events in 2011 too)
• Vapourtec users reach 50 publications (plus 5 more in this issue !)
• Flow Chemistry on TV !
• Plus a good collection of new publications
• Two comprehensive review articles give a great “state of play” of the continuous flow field

Automation, integration and remote access

Date: September 2011

Included in this newsletter:

• A new Vapourtec remote control and automation facility
• More gas/liquid chemistry
• The new Journal of Flow Chemistry is now launched
• Plus photolysis, polymerisation, and lots more

Inert gas & Inert reactors

Date: July 2011

Included in this newsletter:

• Convenient inert gas blanketing of reagents
• New polymer coated stainless steel tube reactors
• A selection of interesting publications

NEW gas reactor enables hydrogenation, carbonylation in flow

Date: May 2011

Included in this newsletter:

• The new Vapourtec Gas/Liquid Reactor is unveiled
• CSIRO in Australia
• Nitration with fuming nitric acid at 97g/hr
• Total synthesis of Fluoxetine in flow
• Library synthesis of Trisubstituted Pyrrolidines

UV-triggered product collection

Date: March 2011

Included in this newsletter:

• 3 new product announcements including UV Triggered Collection of Product peaks
• A new “Case Study” feature
• A chance to get half-price registration for the Flow Chemistry Congress in Boston
• Lots of new flow publications ranging from azide chemistry through magnetic mixing to RAFT polymerizatio

Inline sensing, collaboration, and a telegram from the Queen

Date: January 2011

Included in this newsletter:

• A special day for Vapourtec
• New academic collaborations announced
• New office to open in Malaysia
• New manifold for inline sensor temperature control
• New tube reactor with heated mixing
• 7 new papers

Open Access flow chemistry

Date: November 2010

Included in this newsletter:

• Flow Ozonolysis
• The NEW Open Access Vapourtec System
• Flow chemistry publications from the last few weeks

Cooled columns and Ultrasound

Date: September 2010

Included in this newsletter:

• Dealing with organometallic reagents
• New Cooled column reactor
• Where and when to see Vapourtec systems in action
• New flow chemistry publications from the last few weeks

Ozonolysis with the Vapourtec Flow Chemistry System

Date: May 2010

Included in this newsletter:

• Ozonolysis in the Vapourtec R series, Vapour Pressure of Solvents at High Temps
• Pumping of BuLi now possible
• Where and when to see Vapourtec systems in action
• 5 new flow chemistry publications from the last few weeks

There will be growth in the spring…

Date: March 2010

This issue’s theme is growth. We have product announcements about being able to do more, details of a new annual Flow Chemistry event, plus more interesting new publications than ever. And some Vapourtec news too.

Flow reactions cooled to -70C !

Date: January 2010

This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

50g/hr nitration with fuming nitric acid in flow !

Date: November 2009

There’s clearly a lot of technology development going on in flow! Below you can see Vapourtec’s announcement of the first true nitration capable flow chemistry system. There are also links to a free webinar demonstrating Mettler Toledo’s ReactIR™ flow cell and publications involving online HPLC (Merck), and online phase separation (University of Cardiff).

When is a tube not a tube ?

Date: September 2009

This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

It’s just a phase…

Date: July 2009

In this issue, we take a look at liquid/liquid biphasic reactions in flow.

Flow chemistry with a Click

Date: May 2009

This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

More flexibility than ever

Date: March 2009

This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

Get more reactions done in less time.

Date: January 2009

The theme for this issue is reaction optimisation. If you have an interest in rapid reaction setup, optimisation, and scaleup, and you would like to produce more in less time, read on.

Flow Synthesis Online

Date: November 2008

This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.